Exploring the Benefits of Alpha Lipoic Acid

• Nothing but active ingredients
• A potent antioxidant*
• Aids in energy production*
• Supports liver function*

Thioctic Acid, also referred to as alpha lipoic acid, is an antioxidant that is made by the body and is present in every one of your body cells, where it plays a pivotal role in making energy.*

A healthy body is pretty efficient at making enough thioctic acid to meet the body’s needs. While some antioxidants will only work in water (like vitamin C) or in fat (like vitamin E) due to solubility conditions, thioctic acid is both water and fat soluble, giving it the advantage of protecting all body regions and tissue types from the oxidative damage caused by free radicals. It also recharges other antioxidants to prolong their activity.*

In terms of energy production, thioctic acid is thought to reduce mitochondrial decay and boost energy output. It also functions as a co-factor in enzymes responsible for converting food into usable energy.*

In addition, thioctic acid promotes growth of liver cells, safeguards the kidneys and liver from damage caused by some chemicals found in medications, and helps to expel heavy metals from the body.*

Ingredients
Thioctic acid (R-alpha lipoic acid), gelatin (bovine) capsule

Suggested Use
Adults and children 12 more years of age, take 3 capsules daily or as directed by a healthcare professional. Take with or before a meal to prevent discomfort.

Store at room temperature. Keep out of reach of children.

Frequently Asked Questions
Q: What is the capsule size?
A: Capsule size 1.

Q; What type of capsule does this product come in?
A; This comes in a gelatin capsule. The gelatin is derived from bovine hide (beef skin).

Why Choose Us? With over three decades of unparalleled experience in the health and wellness industry, Dr. Clark Store stands out as a beacon of trust and quality. Unlike others, we are the actual manufacturers who take pride in our craft, overseeing the entire production process to ensure that each bottle meets our high standards. With more than 31 years of expertise and over 10 million bottles produced, you can rest assured that you're choosing a partner dedicated to authentic wellness. We don’t outsource to the lowest bidder.

Guaranteed Authenticity: Every batch of Thioctic Acid is carefully sourced and undergoes rigorous testing for ID, purity, potency, and microbiology before, during, and after manufacturing.

Just Pure Ingredients: At Dr. Clark Store, we stand against adulteration. Our rigorous testing reveals that an estimated 30% of bulk supplement powders in the U.S. market contain added fillers and/or come from incorrect species or plant parts. Unlike importers who operate according to FDA 21 CFR 117 and often rely on analyses done by the manufacturer abroad, we conduct thorough tests on all incoming materials in our full-size laboratory, guaranteeing the integrity of our products.

Carrageenan and Surfactant-Free Capsules: FDA regulation 21 CFR 101.100(a)(3)(ii) allows manufacturers to avoid disclosing ingredients in food if present at “insignificant” levels. This is why "Veggie Capsules" may contain carrageenan. Dr. Clark Store ensures the use of only the finest BSE-free gelatin capsules, free from carrageenan, surfactants, and prion risks. Our dedication to purity dates back over 30 years, ensuring safety and quality in line with Dr. Hulda Clark's original vision.

No Magnesium Stearate and No Hidden Processing Aids: True to Dr. Clark's vision, we never use magnesium stearate or any toxic processing aids in our products. Our commitment to transparency means all ingredients are clearly declared on the label, offering you peace of mind and a product you can trust. Again because of FDA’s lacking regulation 21 CFR 101, many brands contain magnesium stearate without it being declared on the label.

Verifiable GMP Certification: Trust is earned, not given. That's why we back up our GMP certification claims with verifiable evidence. Partnering with VeriGMP®, a UL-certified company, we adhere to strict GMP quality systems, ensuring that each product meets the highest standards of manufacturing and quality assurance.

Choose Dr. Clark Store for your supplement needs and experience the purity and authenticity that only comes from a legacy of passion and excellence in natural wellness.

*Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any diseases. As with any dietary supplement, you should consult with a qualified healthcare professional if you are pregnant or nursing, if you have any medical condition, or if you are taking any medication before using this product. Always consult with a healthcare professional before giving supplements to children. Please read full disclaimer here.

Coupon (discount) codes are not applicable on product subscriptions. The subscription price is already discounted from the one time purchase price.

FAQs 

What is Alpha Lipoic Acid?

Alpha Lipoic Acid (ALA) is a naturally occurring antioxidant that plays a crucial role in energy metabolism. It's distinct because it is both water- and fat-soluble, allowing it to work in various parts of the body. Because of its antioxidant properties, ALA helps combat oxidative stress, which can lead to numerous health issues, making it a vital addition to any dietary supplement regimen.

Health Benefits of Alpha Lipoic Acid

One of the significant advantages of taking Alpha Lipoic Acid is its ability to support metabolic functions. It helps in converting glucose into energy, which is essential for maintaining healthy blood sugar levels. This capacity is particularly beneficial for individuals with insulin sensitivity or those seeking to manage their weight more effectively. Therefore, incorporating ALA into your daily routine can potentially enhance overall well-being.

Usage and Dosage Recommendations

When considering Alpha Lipoic Acid supplementation, it's essential to adhere to the recommended dosage, usually around 360 mg per day. However, as with any supplement, it's wise to consult with a healthcare professional before starting. This ensures you tailor the intake to your health needs and conditions. Because ALA is safe for most users, it can be smoothly integrated into your existing vitamins and supplements routine.

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FAQs for ALA

What is Alpha-Lipoic Acid and what are its primary functions?

What is Alpha-Lipoic Acid and what are its primary functions?

Alpha-Lipoic Acid (ALA), also known as thioctic acid, is a naturally occurring compound that serves as a powerful antioxidant in the body. ALA plays a crucial role in mitochondrial energy production by aiding in the conversion of glucose and fatty acids into ATP, the energy currency of cells. It is unique because, unlike many antioxidants, ALA is both water-soluble and fat-soluble, allowing it to work throughout various parts of the body, including the cell membranes and the cytoplasm. This dual solubility enhances its antioxidant activity and supports various physiological functions. ALA is also involved in the regeneration of other important antioxidants such as vitamins C and E, glutathione, and coenzyme Q10, thus contributing to the overall antioxidant defense system. ALA has been shown to support healthy nerve function and improve insulin sensitivity. It is believed to have neuroprotective effects, particularly in conditions like diabetic neuropathy, and may also support brain health by reducing oxidative stress and inflammation (Shay et al., 2009).

What are the potential health benefits of taking Alpha-Lipoic Acid supplements?

Alpha-Lipoic Acid (ALA) supplements have been widely studied for their potential health benefits, particularly in conditions related to oxidative stress and metabolic dysfunction. Some of the most notable benefits include:

• Nerve Health and Diabetic Neuropathy: ALA has shown promise in supporting nerve health, especially in individuals with diabetic neuropathy. Clinical studies have demonstrated that ALA can reduce symptoms like pain, numbness, and tingling in those with nerve damage due to diabetes (Ziegler et al., 1999). It is believed to work by improving blood flow to nerves, neutralizing free radicals, and enhancing nerve regeneration.

• Improved Insulin Sensitivity: ALA may help improve insulin sensitivity, which is essential for managing type 2 diabetes. Research has found that ALA can help reduce insulin resistance, thereby improving glucose metabolism and blood sugar control (Jacob et al., 1999). This effect is particularly beneficial for people with metabolic disorders like obesity and diabetes.

• Oxidative Stress Reduction: ALA’s potent antioxidant properties allow it to combat oxidative stress, which is a contributing factor to many chronic conditions, including cardiovascular disease, neurodegenerative disorders, and aging. By neutralizing free radicals, ALA helps protect cells and tissues from damage, promoting better long-term health (Biewenga, Haenen & Bast, 1997).

• Anti-Aging Effects: Some studies suggest that ALA can help slow down the aging process by improving mitochondrial function and reducing the accumulation of cellular damage caused by free radicals. This could have implications for conditions like Alzheimer’s disease and other age-related cognitive declines (Shay et al., 2009).

• Alpha-Lipoic Acid (ALA) is a potent antioxidant that helps detoxify heavy metals from the body by binding to toxins and facilitating their removal through the body's natural elimination processes.ALA enhances liver function, neutralizes free radicals, and promotes the elimination of heavy metals such as mercury, lead, and arsenic, thereby supporting comprehensive detoxification.

These findings highlight ALA as a versatile supplement with broad therapeutic potential in managing oxidative stress-related conditions, metabolic diseases, and nerve disorders.

Are there any known side effects or risks associated with Alpha-Lipoic Acid supplementation?

While Alpha-Lipoic Acid (ALA) is generally considered safe when used appropriately, there are some potential side effects and risks associated with high doses or prolonged use. Common, mild side effects include:

• Gastrointestinal Issues: Some individuals may experience nausea, stomach upset, or mild diarrhea when taking ALA, especially at higher doses.

• Skin Reactions: Skin rashes and allergic reactions, though rare, have been reported in some cases.

• Hypoglycemia (Low Blood Sugar): Since ALA can improve insulin sensitivity, there is a risk of low blood sugar in individuals who are already taking medications for diabetes, especially insulin or sulfonylureas. Monitoring blood sugar levels is recommended when taking ALA supplements in combination with diabetes medications (Jacob et al., 1999).

As with any supplement, it is essential to consult a healthcare provider before starting ALA supplementation, particularly for individuals with underlying health conditions, pregnant or breastfeeding women, and those who are on medications.

In what forms is Alpha-Lipoic Acid available for consumption?

Alpha-Lipoic Acid is available in several forms for supplementation, making it versatile and accessible for different individuals:

• Capsules and Tablets: These are the most common forms of ALA, with standardized doses ranging from 100 mg to 600 mg per capsule. Oral forms are convenient for daily supplementation and are widely available in health food stores and pharmacies.

• Powders: ALA can also be found in powder form, which allows for flexible dosing and is often used in combination with other supplements or for those who have difficulty swallowing pills.

• Intravenous (IV) Formulations: In certain medical settings, ALA may be administered intravenously, especially in hospital settings for severe conditions like diabetic neuropathy or acute toxicity. IV administration ensures rapid absorption and higher bioavailability compared to oral forms.

• Topical Applications: Some skincare products contain ALA as an ingredient due to its antioxidant properties, aimed at reducing skin aging and promoting skin health.

For general supplementation, oral capsules or tablets are the most commonly used and recommended form.

What is the recommended dosage of Alpha-Lipoic Acid?

The recommended dosage of Alpha-Lipoic Acid (ALA) can vary depending on individual health needs and the specific condition being treated. Generally, doses of 300 to 600 mg per day are considered effective for improving antioxidant defense, supporting nerve health, and enhancing metabolic function. However, it is important to note that some clinical studies have used higher doses (up to 1,800 mg per day) for specific conditions such as diabetic neuropathy (Ziegler et al., 1999).

For general antioxidant support or to improve insulin sensitivity, a typical dosage range is 300–600 mg per day. Individuals with conditions like diabetic neuropathy may be prescribed higher doses, but these should be taken under medical supervision to avoid potential side effects.

It is crucial to follow the recommendations of a healthcare provider for personalized dosage, as individual requirements can vary based on factors like age, underlying health conditions, and concurrent medications.

Can Alpha-Lipoic Acid interact with other medications or supplements?

Answer:

Yes, Alpha-Lipoic Acid (ALA) has the potential to interact with certain medications and supplements, which can alter its effectiveness or cause unwanted side effects. Some known interactions include:

• Diabetes Medications: Since ALA improves insulin sensitivity, it may lower blood sugar levels when taken with medications such as insulin or sulfonylureas. This could lead to hypoglycemia (low blood sugar), so monitoring blood glucose levels is important (Jacob et al., 1999).

• Chemotherapy Drugs: Some studies suggest that ALA may interfere with the effectiveness of certain chemotherapy drugs by reducing oxidative stress, which is part of how chemotherapy works. For this reason, individuals undergoing chemotherapy should consult with their oncologist before using ALA (Shay et al., 2009).

• Thyroid Medications: ALA may affect thyroid hormone levels, especially in individuals with thyroid disorders. It is advisable to consult a healthcare provider before using ALA if you are taking thyroid medications.

As always, individuals should discuss any new supplements with their healthcare provider, especially if they are on prescription medications.

Is Alpha-Lipoic Acid suitable for vegetarians or vegans?

Answer::

Many Alpha-Lipoic Acid supplements are suitable for vegetarians and vegans, as ALA is not derived from animal sources. However, it is important to check product labels for specific details, as some ALA supplements may be encapsulated in gelatin-based capsules, which are not vegan-friendly. Plant-based capsules or tablets made from cellulose are widely available, and these are suitable for those following a vegetarian or vegan diet.

Additionally, certain ALA supplements may be formulated with other ingredients, such as stearates or fillers, so it is essential to verify that these are also plant-derived if avoiding animal products is a priority.

How does Alpha-Lipoic Acid support antioxidant activity compared to other antioxidants?

Answer:

Alpha-Lipoic Acid stands out among antioxidants due to its unique chemical properties. Unlike most antioxidants, which are either water-soluble or fat-soluble, ALA is both water-soluble and fat-soluble. This allows ALA to exert its antioxidant effects throughout the entire body, including within cell membranes, cytoplasm, and mitochondria.

Furthermore, ALA has the ability to regenerate other antioxidants, such as vitamins C and E, which are crucial in neutralizing free radicals. ALA also restores glutathione, one of the body’s most potent endogenous antioxidants, enhancing overall antioxidant capacity (Packer, Witt, & Tritschler, 1995). This regeneration process makes ALA especially valuable in maintaining long-term antioxidant defenses and protecting cells from oxidative stress.

By regenerating other antioxidants and supporting mitochondrial function, ALA provides broader and more sustained protection than other individual antioxidants.

Q9: Are there specific populations that should avoid using Alpha-Lipoic Acid?

Answer:

While Alpha-Lipoic Acid is generally safe for most individuals, certain populations should exercise caution or avoid its use without medical supervision:

• Pregnant or Breastfeeding Women: There is insufficient research on the safety of ALA during pregnancy and breastfeeding. As a precaution, it is recommended that these individuals avoid ALA supplementation unless advised by a healthcare provider.

• Individuals with Thyroid Disorders: ALA may affect thyroid hormone levels and may interact with thyroid medications, potentially altering thyroid function. Those with thyroid conditions should consult their healthcare provider before taking ALA.

• People Undergoing Surgery: ALA’s effects on insulin sensitivity and blood sugar levels could complicate anesthesia or post-operative recovery. It is advisable to discontinue use before surgery and consult a healthcare provider.

As always, individuals should consult with their healthcare provider to determine whether ALA is appropriate for their specific health needs.

Sources:

Biewenga, G. P., Haenen, G. R. M. M., & Bast, A. (1997). The pharmacology of the antioxidant lipoic acid. General Pharmacology: The Vascular System, 29(3), 315–331.

Jacob, S., Ruus, P., Hermann, R., Tritschler, H. J., Maerker, E., Jung, N., … & Arend, M. (1999). Oral α-lipoic acid treatment improves insulin sensitivity in patients with type-2 diabetes: A placebo-controlled trial. Free Radical Biology and Medicine, 27(3–4), 309–314.

Packer, L., Witt, E. H., & Tritschler, H. J. (1995). Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine, 19(2), 227–250.

Shay, K. P., Moreau, R. F., Smith, E. J., Smith, A. R., & Hagen, T. M. (2009). Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential. Biochimica et Biophysica Acta (BBA) - General Subjects, 1790(10), 1149–1160.

Ziegler, D., Hanefeld, M., Ruhnau, K. J., Hasche, H., Lobisch, M., Schütte, K., & Gries, F. A. (1999). Treatment of symptomatic diabetic polyneuropathy with the antioxidant α-lipoic acid: A 3-week multicenter randomized controlled trial (ALADIN Study). Diabetes Care, 22(8), 1296–1301.