The exact cause of chronic fatigue remains elusive, making it harder to diagnose and treat. However, researchers believe multiple factors may contribute to its development. These include:
Viral or Bacterial Infections
Many cases of chronic fatigue appear to develop after viral or bacterial illnesses. Examples include the Epstein-Barr virus, which causes mononucleosis, and certain bacterial infections like Lyme disease.
Immune System Dysfunction
Some scientists suggest that chronic fatigue may be linked to an overactive or malfunctioning immune system, leaving the body feeling perpetually run-down.
Hormonal Imbalances
Abnormal levels of hormones produced by the hypothalamus, pituitary glands, or adrenal glands are sometimes found in individuals with chronic fatigue syndrome. These imbalances may play a role in triggering symptoms.
Physical or Emotional Trauma
Stress from a physical injury, prolonged mental strain, or a major life event (e.g., a bereavement) has been linked to CFS onset in some cases.
Genetics and a combination of lifestyle factors may also play a role, though the specifics vary from person to person.